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  • Ký hiệu PL/XG: 615
    Nhan đề: Is the thrombocytopenia one of useful predictivemarkers of mortality in pediatric shock patients /

DDC 615
Tác giả CN Nguyen, Ngoc Rang
Nhan đề Is the thrombocytopenia one of useful predictivemarkers of mortality in pediatric shock patients / Nguyen Ngoc Rang, Pham Huu Cong
Tóm tắt Present about platelet count is a routine laboratory measure associated with poor outcomes in adult patients with sepsis/septic shock. The aim of this study was to assess the usefulness of platelet count as a predictive marker of mortality in pediatric patients with septic shock. Over an 18-month period, 62 pediatric patients with septic shock had platelet count measured on the first day of PICU admission. The 28 day in-hospital mortality rate was 66% (41/62). Severe thrombocytopenia (≤ 50 x 109/L) was observed in 52.4% (33/62). In all patients, platelet count was independently associated with PICU mortality (OR 0.96, 95% CI 0.94, 0.99). The AUROC for thrombocytopenia to predict mortality was 0.93 (95% CI 0.87, 0.99). The AUROC of PRISM III score and pSOFA score were 0.81 (95% CI, 0.70 – 0.92) and 0.84 (95% CI, 0.74 – 0.94), respectively. Thrombocytopenia was associated with mortality in pediatric patients with septic shock and provides similar prognostic information as the more complex PRISM III and pSOFA scores.
Từ khóa tự do Mortality
Từ khóa tự do Septic Shock
Từ khóa tự do Thrombocytopenia
Từ khóa tự do Pediatrics
Tác giả(bs) CN Pham, Huu Cong
Nguồn trích Tạp chí Nghiên cứu Y học 2020p. 138-144 Số: 12 Tập: 137
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082 |a615
10010|aNguyen, Ngoc Rang
245 |aIs the thrombocytopenia one of useful predictivemarkers of mortality in pediatric shock patients / |cNguyen Ngoc Rang, Pham Huu Cong
520 |aPresent about platelet count is a routine laboratory measure associated with poor outcomes in adult patients with sepsis/septic shock. The aim of this study was to assess the usefulness of platelet count as a predictive marker of mortality in pediatric patients with septic shock. Over an 18-month period, 62 pediatric patients with septic shock had platelet count measured on the first day of PICU admission. The 28 day in-hospital mortality rate was 66% (41/62). Severe thrombocytopenia (≤ 50 x 109/L) was observed in 52.4% (33/62). In all patients, platelet count was independently associated with PICU mortality (OR 0.96, 95% CI 0.94, 0.99). The AUROC for thrombocytopenia to predict mortality was 0.93 (95% CI 0.87, 0.99). The AUROC of PRISM III score and pSOFA score were 0.81 (95% CI, 0.70 – 0.92) and 0.84 (95% CI, 0.74 – 0.94), respectively. Thrombocytopenia was associated with mortality in pediatric patients with septic shock and provides similar prognostic information as the more complex PRISM III and pSOFA scores.
653 |aMortality
653 |aSeptic Shock
653 |aThrombocytopenia
653 |aPediatrics
700 |aPham, Huu Cong
7730 |tTạp chí Nghiên cứu Y học |d2020|gp. 138-144|x2354-080X|v137|i12
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