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Challenging cases in diagnostic clinical microbiology : advanced strategies and techniques / James J. Dunn, Marc Roger Couturier, Audrey N. Schuetz (editor)
Cham : Springer, 2024
252 pages. : illustrations (chiefly color) ; cm.
Ký hiệu phân loại (DDC): 616.9041
This book aims to communicate, educate and inform readers about important facts and new information related to the practice of clinical microbiology and how laboratory testing can be used to provide data impactful to diagnose, treat and manage patients with infectious diseases. This information is important for individual patient outcomes as well as general public health. The book will provide real world examples of how infectious disease diagnostic tests are applied to algorithms to guide the differential diagnosis and facilitate the diagnosis and treatment of patients. Each section of cases based on the type of organisms involved will be preceded by a discussion of the laboratory methods routinely used to diagnose those types of infections. Most importantly, each illustrated case will be structured to include details of the clinical presentation, differential diagnosis, relevant laboratory findings, pathogen identified, and a brief review of other potential etiologies for the clinical syndrome described. The field of clinical microbiology has evolved considerably over the last couple of decades and the technological advances continue to come at a rapid pace. By incorporating these advancements into the clinical cases, readers will gain a greater understanding of the intricacies and nuances of the performance and utility of these newer tests, as well as how the results should be interpreted for various patient populations. Readers will acquire a wide breadth of knowledge through comprehensive reading of these cases and will benefit greatly from increased familiarity with the practice of clinical infectious disease diagnostics. Envisioned as an instructional text for those already practicing in or training in the field of clinical microbiology, this book will serve clinical pathologists, clinical microbiologists, allied healthcare professionals and physicians, as well as medical students, clinical laboratory scientists and trainees, medical residents, and infectious disease and microbiology fellows. It will be a tool to learn about and enhance skills in the discipline through presentation and discussion of cases and methods. While trainees such as medical students, residents, and fellows will benefit by thinking about the whole process from patient to lab to appropriate treatment- following the structure of board exams- those already in the field will broaden their knowledge base with information on the most up-to-date testing methods and algorithms used in the clinical microbiology lab
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Nanotechnology approaches for global infectious diseases / Ameya R. Kirtane, Malvika Verma, Paramesh Karandikar , Jennifer Furin, Robert Langer , Giovanni Traverso // NATURE NANOTECHNOLOGY; . - . - p.369-371. - ISSN:
Ký hiệu phân loại (DDC): 610.42
Infectious diseases are a major driver of morbidity and mortality globally. Treatment of malaria, tuberculosis and human immunodeficiency virus infection are particularly challenging, as indicated by the ongoing transmission and high mortality associated with these diseases. The formulation of new and existing drugs in nano-sized carriers promises to overcome sev- eral challenges associated with the treatment of these diseases, including low on-target bioavailability, sub-therapeutic drug accumulation in microbial sanctuaries and reservoirs, and low patient adherence due to drug-related toxicities and extended therapeutic regimens. Further, nanocarriers can be used for formulating vaccines, which represent a major weapon in our fight against infectious diseases. Here we review the current burden of infectious diseases with a focus on major drivers of morbid- ity and mortality. We then highlight how nanotechnology could aid in improving existing treatment modalities. We summarize our progress so far and outline potential future directions to maximize the impact of nanotechnology on the global population.
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