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Is the thrombocytopenia one of useful predictivemarkers of mortality in pediatric shock patients / Nguyen Ngoc Rang, Pham Huu Cong // Tạp chí Nghiên cứu Y học . - 2020. - p. 138-144. - ISSN: 2354-080X



Ký hiệu phân loại (DDC): 615
Present about platelet count is a routine laboratory measure associated with poor outcomes in adult patients with sepsis/septic shock. The aim of this study was to assess the usefulness of platelet count as a predictive marker of mortality in pediatric patients with septic shock. Over an 18-month period, 62 pediatric patients with septic shock had platelet count measured on the first day of PICU admission. The 28 day in-hospital mortality rate was 66% (41/62). Severe thrombocytopenia (≤ 50 x 109/L) was observed in 52.4% (33/62). In all patients, platelet count was independently associated with PICU mortality (OR 0.96, 95% CI 0.94, 0.99). The AUROC for thrombocytopenia to predict mortality was 0.93 (95% CI 0.87, 0.99). The AUROC of PRISM III score and pSOFA score were 0.81 (95% CI, 0.70 – 0.92) and 0.84 (95% CI, 0.74 – 0.94), respectively. Thrombocytopenia was associated with mortality in pediatric patients with septic shock and provides similar prognostic information as the more complex PRISM III and pSOFA scores.
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