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    Nhan đề: Transdermal patches: history, development and pharmacology /
DDC 615
Nhan đề Transdermal patches: history, development and pharmacology / Michael N. Pastore ... [et al]
Mô tả vật lý 31 p. ;
Tóm tắt Transdermal patches are now widely used as cosmetic, topical and transdermal delivery systems. These patches represent a key outcome from the growth in skin science, technology and expertise developed through trial and error, clinical observation and evidence-based studies that date back to the first existing human records. This review begins with the earliest topical therapies and traces topical delivery to the present-day transdermal patches, describing along the way the initial trials, devices and drug delivery systems that underpin current transdermal patches and their actives. This is followed by consideration of the evolution in the various patch designs and their limitations as well as requirements for actives to be used for transdermal delivery. The properties of and issues associated with the use of currently marketed products, such as variability, safety and regulatory aspects, are then described. The review concludes by examining future prospects for transdermal patches and drug delivery systems, such as the combination of active delivery systems with patches, minimally invasive microneedle patches and cutaneous solutions, including metered-dose systems.
Từ khóa tự do Pharmacology
Từ khóa tự do Examining future prospects
Từ khóa tự do Minimally invasive microneedle
Tác giả(bs) CN Horstmann, Michael
Tác giả(bs) CN Pastore, Michael N.
Tác giả(bs) CN Kalia, Yogeshvar N.
Tác giả(bs) CN Roberts, Michael S.
Nguồn trích British Journal of PharmacologyUnited Kingdom : Wiley-Blackwell, 2015Vol. 172, Issue 9 (May 2015), p. 2179-2209
Tệp tin điện tử https://doi.org/10.1111/bph.13059
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245 |aTransdermal patches: history, development and pharmacology / |cMichael N. Pastore ... [et al]
300 |a31 p. ;
520 |aTransdermal patches are now widely used as cosmetic, topical and transdermal delivery systems. These patches represent a key outcome from the growth in skin science, technology and expertise developed through trial and error, clinical observation and evidence-based studies that date back to the first existing human records. This review begins with the earliest topical therapies and traces topical delivery to the present-day transdermal patches, describing along the way the initial trials, devices and drug delivery systems that underpin current transdermal patches and their actives. This is followed by consideration of the evolution in the various patch designs and their limitations as well as requirements for actives to be used for transdermal delivery. The properties of and issues associated with the use of currently marketed products, such as variability, safety and regulatory aspects, are then described. The review concludes by examining future prospects for transdermal patches and drug delivery systems, such as the combination of active delivery systems with patches, minimally invasive microneedle patches and cutaneous solutions, including metered-dose systems.
653 |aPharmacology
653 |aExamining future prospects
653 |aMinimally invasive microneedle
700 |aHorstmann, Michael
700 |aPastore, Michael N.
700 |aKalia, Yogeshvar N.
700|aRoberts, Michael S.
773|tBritish Journal of Pharmacology|dUnited Kingdom : Wiley-Blackwell, 2015|gVol. 172, Issue 9 (May 2015), p. 2179-2209|x1476-5381
856|uhttps://doi.org/10.1111/bph.13059
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