|
DDC
| 615 | |
Tác giả CN
| Trần, Ngọc Luân | |
Nhan đề
| Xây dựng qui trình phân tích một số Glucocorticoid ngụy tạo trong chế phẩm dược liệu bằng phương pháp UHPLC-UV-Vis / Trần Ngọc Luân, Đỗ Châu Minh Vĩnh Thọ, Nguyễn Đức Tuấn | |
Tóm tắt
| A simple reversed phase UHPLC-UV-Vis method was developed for simultaneous determination of prednisolone, methylprednisolone, betamethasone, and dexamethasone acetate adulterated in herbal medicines used for treatment of rheumatoid arthritis. The method was estalished as: Column - Thermo Acclamide Polar C16 (4.6 x 250 mm; 5µm); Mobile phase - acetonitrile and water in gradient mode; Flow rate - 1 ml/min; Detector – UV (240 nm). Validated in observane to the AOAC guidelines, the proposed method showed to meet well the all the requirements: suitability for UHPLC system, selectivity, linearity range (R2 > 0.995), accuracy (recoveries in the range of 90% - 107%), and precision (RSD < 5.3%), and high sensitivity (LOD: 0.32 ppm, LOQ: 1.3 ppm). For practical tets, these four glucocorticoids were analyized in 30 available herbal products; of these five were found illegally aldulterated with corticoids. | |
Thuật ngữ chủ đề
| Nghiên cứu - Kỹ thuật -- Việt Nam | |
Từ khóa tự do
| Glucocorticoid | |
Từ khóa tự do
| UHPLC-UV-Vis | |
Tác giả(bs) CN
| Đỗ, Châu Minh Vĩnh Thọ | |
Nguồn trích
| Tạp chí Dược học 2018tr. 41-44
Số: 02 |
| |
000
| 00000nab#a2200000ui#4500 |
|---|
| 001 | 18906 |
|---|
| 002 | 9 |
|---|
| 004 | 7453CBDA-F634-474A-B60A-E651BD2ADB1B |
|---|
| 005 | 201912131138 |
|---|
| 008 | 081223s vm| vie |
|---|
| 009 | 1 0 |
|---|
| 039 | |y20191213113809|zthienvan |
|---|
| 082 | |a615 |
|---|
| 100 | |aTrần, Ngọc Luân |
|---|
| 245 | |aXây dựng qui trình phân tích một số Glucocorticoid ngụy tạo trong chế phẩm dược liệu bằng phương pháp UHPLC-UV-Vis / |cTrần Ngọc Luân, Đỗ Châu Minh Vĩnh Thọ, Nguyễn Đức Tuấn |
|---|
| 520 | |aA simple reversed phase UHPLC-UV-Vis method was developed for simultaneous determination of prednisolone, methylprednisolone, betamethasone, and dexamethasone acetate adulterated in herbal medicines used for treatment of rheumatoid arthritis. The method was estalished as: Column - Thermo Acclamide Polar C16 (4.6 x 250 mm; 5µm); Mobile phase - acetonitrile and water in gradient mode; Flow rate - 1 ml/min; Detector – UV (240 nm). Validated in observane to the AOAC guidelines, the proposed method showed to meet well the all the requirements: suitability for UHPLC system, selectivity, linearity range (R2 > 0.995), accuracy (recoveries in the range of 90% - 107%), and precision (RSD < 5.3%), and high sensitivity (LOD: 0.32 ppm, LOQ: 1.3 ppm). For practical tets, these four glucocorticoids were analyized in 30 available herbal products; of these five were found illegally aldulterated with corticoids. |
|---|
| 650 | |aNghiên cứu - Kỹ thuật |z Việt Nam |
|---|
| 653 | |aGlucocorticoid |
|---|
| 653 | |aUHPLC-UV-Vis |
|---|
| 700 | |aĐỗ, Châu Minh Vĩnh Thọ |
|---|
| 773 | |tTạp chí Dược học |d2018|gtr. 41-44|i02 |
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| 890 | |c1|a0|b0|d3 |
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