|
DDC
| 615 | |
Tác giả CN
| Phan, Cường Huy | |
Nhan đề
| Tổng hợp, hoạt tính kháng khuẩn và kháng nấm của dẫn chất N - thế acid anthranilic / Phan Cường Huy,Phạm Cảnh Em, Đỗ Thị Thúy, Trương Ngọc Tuyền | |
Tóm tắt
| Regarding anthranilic acid as a frequent constituent of many bioactive compounds possessing wide ranges of biological activities, and the nucleus of anthranilic acid is the biochemical precursor of amino acids themselves, their derivatives several alkaloids as well, four N-substituted derivatives of anthranilic acid were synthesized in good yields. The structures of the synthesized derivatives were confirmed by IR, 1H-NMR and MS. In bioactivity, the synthesized derivatives were evaluated for in vitro antifungal and antimicrobial properties on 5 fungal and 4 microbial strains. These derivatives showed no effect on bacteria but average inhibition on T.mentagrophytes and M. gypseum (compound 1 and 4). | |
Thuật ngữ chủ đề
| Nghiên cứu - Kỹ Thuật -- Việt Nam | |
Từ khóa tự do
| Acid Anthranilic | |
Từ khóa tự do
| Kháng khuẩn và kháng nấm | |
Tác giả(bs) CN
| Phạm Cảnh Em | |
Nguồn trích
| Tạp chí Dược học 2018tr. 29-32
Số: 03 |
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000
| 00000nab#a2200000ui#4500 |
|---|
| 001 | 18868 |
|---|
| 002 | 9 |
|---|
| 004 | 577F6791-2B0D-496A-B9CE-18B7E48E880C |
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| 005 | 201912121604 |
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| 008 | 081223s vm| vie |
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| 009 | 1 0 |
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| 039 | |y20191212160427|zthienvan |
|---|
| 082 | |a615 |
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| 100 | |aPhan, Cường Huy |
|---|
| 245 | |aTổng hợp, hoạt tính kháng khuẩn và kháng nấm của dẫn chất N - thế acid anthranilic / |cPhan Cường Huy,Phạm Cảnh Em, Đỗ Thị Thúy, Trương Ngọc Tuyền |
|---|
| 520 | |aRegarding anthranilic acid as a frequent constituent of many bioactive compounds possessing wide ranges of biological activities, and the nucleus of anthranilic acid is the biochemical precursor of amino acids themselves, their derivatives several alkaloids as well, four N-substituted derivatives of anthranilic acid were synthesized in good yields. The structures of the synthesized derivatives were confirmed by IR, 1H-NMR and MS. In bioactivity, the synthesized derivatives were evaluated for in vitro antifungal and antimicrobial properties on 5 fungal and 4 microbial strains. These derivatives showed no effect on bacteria but average inhibition on T.mentagrophytes and M. gypseum (compound 1 and 4). |
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| 650 | |aNghiên cứu - Kỹ Thuật |z Việt Nam |
|---|
| 653 | |aAcid Anthranilic |
|---|
| 653 | |aKháng khuẩn và kháng nấm |
|---|
| 700 | |aPhạm Cảnh Em |
|---|
| 773 | |tTạp chí Dược học |d2018|gtr. 29-32|i03 |
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| 890 | |c1|a0|b0|d4 |
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