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  • Bài trích
  • Ký hiệu PL/XG: 615
    Nhan đề: Nghiên cứu phân lập Andrographolid làm chất đối chiếu từ cây xuyên tâm liên (Andrographis paniculata (Burm.f.) Nees) /
DDC 615
Tác giả CN Lữ, Thị Kim Chi
Nhan đề Nghiên cứu phân lập Andrographolid làm chất đối chiếu từ cây xuyên tâm liên (Andrographis paniculata (Burm.f.) Nees) / Lữ Thị Kim Chi, Huỳnh Tự Thuật, Nguyễn Ngọc Vinh
Tóm tắt Andrographolid, as a natural biological active, was isolated from Andrographis paniculata (Burm.f.) Nees (Acanthaceae) and purified to the purtity of 98.03%. Its structure was elucidated by UV-Vis, IR, MS, 1HNMR, 13CNMR. In addition, an HPLC method was validated for analysis of andrographolid. The calibration curves were established by six replicate experiments (with purified andrographolid) demontrated a good linear regression over a range of 120,06 – 283.13mg/ml (R2 = 0.9996); the precision RSD was less than 2%; the accuracy ranged from 99.01 – 101.24%. This proved the obtained andrographolid was fairly corresponding to the certified reference material of USP in terms of content, and therefore, may be established as reference standard for quality control and research of the plant.
Thuật ngữ chủ đề Nghiên cứu - Kỹ Thuật -- Việt Nam
Từ khóa tự do Andrographolid
Từ khóa tự do Cây Xuyên Tâm Liên
Tác giả(bs) CN Huỳnh, Tự Thuật
Nguồn trích Tạp chí Dược học 2018tr. 49-52 Số: 03
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00118839
0029
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005201912121319
008081223s vm| vie
0091 0
039|y20191212131958|zthienvan
082 |a615
100 |aLữ, Thị Kim Chi
245 |aNghiên cứu phân lập Andrographolid làm chất đối chiếu từ cây xuyên tâm liên (Andrographis paniculata (Burm.f.) Nees) / |cLữ Thị Kim Chi, Huỳnh Tự Thuật, Nguyễn Ngọc Vinh
520 |aAndrographolid, as a natural biological active, was isolated from Andrographis paniculata (Burm.f.) Nees (Acanthaceae) and purified to the purtity of 98.03%. Its structure was elucidated by UV-Vis, IR, MS, 1HNMR, 13CNMR. In addition, an HPLC method was validated for analysis of andrographolid. The calibration curves were established by six replicate experiments (with purified andrographolid) demontrated a good linear regression over a range of 120,06 – 283.13mg/ml (R2 = 0.9996); the precision RSD was less than 2%; the accuracy ranged from 99.01 – 101.24%. This proved the obtained andrographolid was fairly corresponding to the certified reference material of USP in terms of content, and therefore, may be established as reference standard for quality control and research of the plant.
650 |aNghiên cứu - Kỹ Thuật |z Việt Nam
653 |aAndrographolid
653 |aCây Xuyên Tâm Liên
700 |aHuỳnh, Tự Thuật
773 |tTạp chí Dược học |d2018|gtr. 49-52|i03
890|c1|a0|b0|d4
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