DDC
| 615 |
Tác giả CN
| Nguyễn, Thị Chi |
Nhan đề
| Nghiên cứu khả năng kháng oxy hóa và ức chế Enzym α-Glucosidase của cao chiết từ lá cây lá Đắng (Vernonia amygdalina Del.), họ Cúc (Asteraceae) / Nguyễn Thị Chi, Phạm Việt Trang, Lê Xuân Tiến, Nguyễn Văn Thanh |
Tóm tắt
| The plant Vernonia amygdalina Del. (Asteraceae) (“lá đắng” - bitter leaf plant) was studied for antioxidant activity and inhibitive power on α-glucosidase enzyme. The dichloromethane extracts showed the best in bioactivities in question. The extraction was investigated for high efficiency and potential inhibitivity on α-glucosidase enzyme. Finally, the extration was optimized as: the plant powders were extracted three times, once with ethanol 40% (v/v), solid-to-liquid ratio of 1/5 (w/v) at 50oC for 40 min. The obtained extracts showed antioxidant activity (IC50 = 51.9 μg/mL) and good inhibitivity on α-glucosidase enzyme (IC50 = 480 μg/mL), much higher than the ethanol and aqueous extracts.
|
Từ khóa tự do
| Enzym α-Glucosidase |
Từ khóa tự do
| Kháng oxy hóa |
Từ khóa tự do
| Lá Đắng |
Tác giả(bs) CN
| Phạm, Việt Trang |
Nguồn trích
| Tạp chí Dược học 2018tr. 25-29
Số: 07 |
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000
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001 | 18717 |
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002 | 9 |
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004 | FC032A21-F61D-4229-B4D3-0CFEA3F4DE09 |
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005 | 201912061524 |
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008 | 081223s vm| vie |
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009 | 1 0 |
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039 | |y20191206152419|zthienvan |
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082 | |a615 |
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100 | |aNguyễn, Thị Chi |
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245 | |aNghiên cứu khả năng kháng oxy hóa và ức chế Enzym α-Glucosidase của cao chiết từ lá cây lá Đắng (Vernonia amygdalina Del.), họ Cúc (Asteraceae) / |cNguyễn Thị Chi, Phạm Việt Trang, Lê Xuân Tiến, Nguyễn Văn Thanh |
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520 | |a The plant Vernonia amygdalina Del. (Asteraceae) (“lá đắng” - bitter leaf plant) was studied for antioxidant activity and inhibitive power on α-glucosidase enzyme. The dichloromethane extracts showed the best in bioactivities in question. The extraction was investigated for high efficiency and potential inhibitivity on α-glucosidase enzyme. Finally, the extration was optimized as: the plant powders were extracted three times, once with ethanol 40% (v/v), solid-to-liquid ratio of 1/5 (w/v) at 50oC for 40 min. The obtained extracts showed antioxidant activity (IC50 = 51.9 μg/mL) and good inhibitivity on α-glucosidase enzyme (IC50 = 480 μg/mL), much higher than the ethanol and aqueous extracts.
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653 | |aEnzym α-Glucosidase |
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653 | |aKháng oxy hóa |
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653 | |aLá Đắng |
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700 | |aPhạm, Việt Trang |
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773 | |tTạp chí Dược học |d2018|gtr. 25-29|i07 |
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890 | |c1|a0|b0|d5 |
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