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  • Bài trích
  • Ký hiệu PL/XG: 615
    Nhan đề: Biến cố trên Thận và trên thính giác trong điều trị Lao đa kháng ghi nhận qua hoạt động giám sát tích cực tại Việt Nam /
DDC 615
Tác giả CN Nguyễn, Thị Thủy
Nhan đề Biến cố trên Thận và trên thính giác trong điều trị Lao đa kháng ghi nhận qua hoạt động giám sát tích cực tại Việt Nam / Nguyễn Thị Thủy, Cao Thị Thu Huyền, Nguyễn Bảo Ngọc, Dương Văn Quang, Vũ Đình Hòa, Nguyễn Hoàng Anh, Nguyễn Viết Nhung
Tóm tắt Ototoxity and nephrotoxicity as the main causes of adverse events of injectable anti-tuberculosis drugs were investigated by a prospective study based on a Cohort Event Monitoring (CEM) program in 9 sentinel sites in Vietnam from April 2014 to December 2016. The study involved a cohort of 659 of MDR-TB patients. Of these, 7.4% experienced at least one renal adverse event each, and 15.2% were affected by ototoxicity during treatment. Multivariate regression analysis revealed a history of existing renal/hearing problems related to nephrotoxicity/ototoxicity, respectively. Meanwhile, it was the daily dose of the injectable drugs that appeared as a risk factor to both types of the AEs. In Vietnam, nephrotoxicity and ototoxicity were quite common in MDR-TB treatment, therefore, certainly resposonsible for the MDR-TB relared renal failure and irreversible hearing loss. The findings of the related factors to nephrotoxicity and ototoxicity by this study posed weight on patient history investigation, baseline examination and close monitoring of renal function and audiometry in patients treated by MDR-TB regimens, especially those consisting of injectable drugs of the kind.
Thuật ngữ chủ đề Nghiên cứu kỹ thuật --Việt Nam
Từ khóa tự do Lao đa kháng
Từ khóa tự do Thận
Từ khóa tự do Thính giác
Tác giả(bs) CN Cao, Thị Thu Huyền
Nguồn trích Tạp chí Dược học 2018tr. 11-15 Số: 11
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039|y20191205094347|zthienvan
082 |a615
100 |aNguyễn, Thị Thủy
245 |aBiến cố trên Thận và trên thính giác trong điều trị Lao đa kháng ghi nhận qua hoạt động giám sát tích cực tại Việt Nam / |cNguyễn Thị Thủy, Cao Thị Thu Huyền, Nguyễn Bảo Ngọc, Dương Văn Quang, Vũ Đình Hòa, Nguyễn Hoàng Anh, Nguyễn Viết Nhung
520 |aOtotoxity and nephrotoxicity as the main causes of adverse events of injectable anti-tuberculosis drugs were investigated by a prospective study based on a Cohort Event Monitoring (CEM) program in 9 sentinel sites in Vietnam from April 2014 to December 2016. The study involved a cohort of 659 of MDR-TB patients. Of these, 7.4% experienced at least one renal adverse event each, and 15.2% were affected by ototoxicity during treatment. Multivariate regression analysis revealed a history of existing renal/hearing problems related to nephrotoxicity/ototoxicity, respectively. Meanwhile, it was the daily dose of the injectable drugs that appeared as a risk factor to both types of the AEs. In Vietnam, nephrotoxicity and ototoxicity were quite common in MDR-TB treatment, therefore, certainly resposonsible for the MDR-TB relared renal failure and irreversible hearing loss. The findings of the related factors to nephrotoxicity and ototoxicity by this study posed weight on patient history investigation, baseline examination and close monitoring of renal function and audiometry in patients treated by MDR-TB regimens, especially those consisting of injectable drugs of the kind.
650 |aNghiên cứu kỹ thuật |zViệt Nam
653 |aLao đa kháng
653 |aThận
653 |aThính giác
700 |aCao, Thị Thu Huyền
773 |tTạp chí Dược học |d2018|gtr. 11-15|i11
890|c1|a0|b0|d5
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