|
DDC
| 615 | |
Tác giả CN
| Nguyễn, Ngọc Chiến | |
Nhan đề
| Nghiên cứu bào chế Hydrogel chứa tiểu phân Niosome Tadalafil / Nguyễn Ngọc Chiến, Phạm Thị Mai Anh | |
Tóm tắt
| Tadalafil loaded niosomes were formed by ethanol injection method. Suspension were prepared with tadalafil as the core, span 60 and cholesterol as coating materials and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) as stabilizer. The oil phase containing Span 60, cholesterol and tadalafil was injected into a solution of TPGS 0.2% as the water phase by a high speed mixer at 300 rpm for 2 minutes at 650C. The obtained suspensions were stirred at 150 rpm for 1 hr to evaporate ethanol. The final hydogels were achieved by dispersion of xanthan gum and a permeability enhancer into the tadalafil niosomes. The drug release of the formulated hydrogels reached up to 21.11 ± 0.40% after 6 hours as measured with Franz diffusion cells. | |
Thuật ngữ chủ đề
| Nghiên cứu kỹ thuật--Việt Nam | |
Từ khóa tự do
| Hydrogel | |
Từ khóa tự do
| Niosome Tadalafil | |
Từ khóa tự do
| Tiểu phân | |
Tác giả(bs) CN
| Phạm, Thị Mai Anh | |
Nguồn trích
| Tạp chí Dược học 2019tr. 13-16,35
Số: 01 |
| |
000
| 00000nab#a2200000ui#4500 |
|---|
| 001 | 18571 |
|---|
| 002 | 9 |
|---|
| 004 | D6642C19-0A33-4290-BC97-49ACF6F9A924 |
|---|
| 005 | 201912040915 |
|---|
| 008 | 081223s vm| vie |
|---|
| 009 | 1 0 |
|---|
| 039 | |y20191204091541|zthienvan |
|---|
| 082 | |a615 |
|---|
| 100 | |aNguyễn, Ngọc Chiến |
|---|
| 245 | |aNghiên cứu bào chế Hydrogel chứa tiểu phân Niosome Tadalafil / |cNguyễn Ngọc Chiến, Phạm Thị Mai Anh |
|---|
| 520 | |aTadalafil loaded niosomes were formed by ethanol injection method. Suspension were prepared with tadalafil as the core, span 60 and cholesterol as coating materials and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) as stabilizer. The oil phase containing Span 60, cholesterol and tadalafil was injected into a solution of TPGS 0.2% as the water phase by a high speed mixer at 300 rpm for 2 minutes at 650C. The obtained suspensions were stirred at 150 rpm for 1 hr to evaporate ethanol. The final hydogels were achieved by dispersion of xanthan gum and a permeability enhancer into the tadalafil niosomes. The drug release of the formulated hydrogels reached up to 21.11 ± 0.40% after 6 hours as measured with Franz diffusion cells. |
|---|
| 650 | |aNghiên cứu kỹ thuật|zViệt Nam |
|---|
| 653 | |aHydrogel |
|---|
| 653 | |aNiosome Tadalafil |
|---|
| 653 | |aTiểu phân |
|---|
| 700 | |aPhạm, Thị Mai Anh |
|---|
| 773 | |tTạp chí Dược học |d2019|gtr. 13-16,35|i01 |
|---|
| 890 | |c1|a0|b0|d12 |
|---|
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