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  • Ký hiệu PL/XG: 616.8527
    Nhan đề: Clinical Profiles of Major Depressive Disorder Based on Age Groups :
DDC 616.8527
Nhan đề Clinical Profiles of Major Depressive Disorder Based on Age Groups : A Cross-Sectional Study, Vietnam / Phi Nguyen Yen Ho, Tho Quoc Truong, Tram Nhu Thanh Nguyen, Tram Ly Bich Nguyen, Manh Xuan Bui, Ngoc Anh Tran, Chau Thi Minh Pham, Phu Thi Nguyen, Phan Ngoc Ai, Nghia Trung Tran, Linh Tich Ngo
Tóm tắt Introduction: Depression is a common mental disorder; however, no study has investigated adolescent and late-life depression in Vietnam, and little has been done to compare the clinical characteristics among age groups of patients with this condition in the literature. Therefore, the study aims to examine the differences in symptom presentation among adolescents, adults, and the elderly with major depressive disorder (MDD). Methods: A total of 238 patients diagnosed with MDD according to the DSM-5, including 43 aged 10 to 17 years old, 74 aged 18 to 59 years old, and 121 aged 60 and older, were recruited in a cross-sectional study from March to August 2022 at three psychiatric clinics in Ho Chi Minh City. The eligible participant completed an epidemiological questionnaire. Results: All participants exhibited depressed mood, and 58.8% admitted to having suicidal ideation, with an alarming rate among adolescents (72.1%). Adolescents were less likely to experience the symptoms of interest decrease, appetite problems, insomnia, fatigue, and anxious distress than these other groups (p < 0.05). The pattern of symptom profiles in depressed adults largely remained the same in the older patients, except for psychomotor retardation and concentration problems, in which the latter were less likely to exhibit these symptoms compared to the first one (p<0.001). Conclusion: Adolescents appear to experience fewer depressive symptoms than adults and the elderly, while the two later groups show similar clinical presentations. Therefore, the differences in symptoms across age groups necessitate an individual approach and management by clinicians.
Từ khóa tự do Clinical characteristic
Từ khóa tự do Major depressive disorder
Từ khóa tự do Psychiatric facility
Từ khóa tự do Age groups
Tác giả(bs) CN Ho, Nguyen Phi Yen
Tác giả(bs) CN Nguyen, Nhu Thanh Tram
Tác giả(bs) CN Truong, Quoc Tho
Tác giả(bs) CN Bui, Xuan Manh
Tác giả(bs) CN Ngo, Tich Linh
Tác giả(bs) CN Tran, Trung Nghia
Tác giả(bs) CN Nguyen, Ly Bich Tram
Tác giả(bs) CN Nguyen, Thi Phu
Tác giả(bs) CN Pham, Thi Minh Chau
Tác giả(bs) CN Phan, Ngoc Ai
Tác giả(bs) CN Tran, Ngoc Anh
Nguồn trích MedPharmRes 2023tr. 109-114 Số: 3 Tập: 7
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082 |a616.8527
245 |aClinical Profiles of Major Depressive Disorder Based on Age Groups : |bA Cross-Sectional Study, Vietnam / |cPhi Nguyen Yen Ho, Tho Quoc Truong, Tram Nhu Thanh Nguyen, Tram Ly Bich Nguyen, Manh Xuan Bui, Ngoc Anh Tran, Chau Thi Minh Pham, Phu Thi Nguyen, Phan Ngoc Ai, Nghia Trung Tran, Linh Tich Ngo
520 |aIntroduction: Depression is a common mental disorder; however, no study has investigated adolescent and late-life depression in Vietnam, and little has been done to compare the clinical characteristics among age groups of patients with this condition in the literature. Therefore, the study aims to examine the differences in symptom presentation among adolescents, adults, and the elderly with major depressive disorder (MDD). Methods: A total of 238 patients diagnosed with MDD according to the DSM-5, including 43 aged 10 to 17 years old, 74 aged 18 to 59 years old, and 121 aged 60 and older, were recruited in a cross-sectional study from March to August 2022 at three psychiatric clinics in Ho Chi Minh City. The eligible participant completed an epidemiological questionnaire. Results: All participants exhibited depressed mood, and 58.8% admitted to having suicidal ideation, with an alarming rate among adolescents (72.1%). Adolescents were less likely to experience the symptoms of interest decrease, appetite problems, insomnia, fatigue, and anxious distress than these other groups (p < 0.05). The pattern of symptom profiles in depressed adults largely remained the same in the older patients, except for psychomotor retardation and concentration problems, in which the latter were less likely to exhibit these symptoms compared to the first one (p<0.001). Conclusion: Adolescents appear to experience fewer depressive symptoms than adults and the elderly, while the two later groups show similar clinical presentations. Therefore, the differences in symptoms across age groups necessitate an individual approach and management by clinicians.
653 |aClinical characteristic
653 |aMajor depressive disorder
653 |aPsychiatric facility
653 |aAge groups
700 |aHo, Nguyen Phi Yen
700 |aNguyen, Nhu Thanh Tram
700 |aTruong, Quoc Tho
700|aBui, Xuan Manh
700|aNgo, Tich Linh
700|aTran, Trung Nghia
700|aNguyen, Ly Bich Tram
700|aNguyen, Thi Phu
700|aPham, Thi Minh Chau
700|aPhan, Ngoc Ai
700|aTran, Ngoc Anh
7730 |tMedPharmRes |d2023|gtr. 109-114|x2615-9139|v7|i3
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