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Biomolecular forms and functions : a celebration of 50 years of the Ramachandran map / Manju Bansal, Narayanaswamy Srinivasan (editor)
Hackensack, NJ : World Scientific Pub. Co. Inc., 2013
xii, 502 pages. : illustrations ; 24 cm.
Ký hiệu phân loại (DDC): 572.862
Understanding the functions and properties of molecules in living systems requires a detailed knowledge of their three-dimensional structures and the conformational variability that allows them to adopt multiple functional forms. Interpreting biological systems in the language of three-dimensional structures is of fundamental importance and innumerable research groups around the world are working in this area. This book is a compilation of articles describing attempts at understanding the intricacies of biological systems through the structures of and interactions between their constituent molecules
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Conformational proteomics of macromolecular architecture : approaching the structure of large molecular assemblies and their mechanisms of action / R. Holland Cheng, Lena Hammar (editor)
Singapore : World Scientific Pub., 2004
xi, 420 pages. : illustrations (some color) ; 24 cm.
Ký hiệu phân loại (DDC): 572.67
Biological processes involving large macromolecular assemblies arethought to be a dynamic consequence of cooperativity andmetastability. The folding of a peptide chain creates localenvironments from which "activity" can emerge. In the same way, theassembly of large molecular complexes creates dynamic features thatwould only be feasible in a large construct. The biologicalimplications of such adaptation will be explored as it applies to thestatic quasisymmetry situations, as well as to the dynamics ofstructural transitions. The current wealth of solved high-resolutioncomplex structures makes
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