Dòng Nội dung
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Clinical characteristics, interventions and outcomes of acute lower gastrointestinal bleeding : A multicenter study in Vietnam / Uyen Pham Phuong Vo, Na Le To, Ly Thi Kim Le, Cong Hong Minh Vo and Duc Trong Quach // MedPharmRes . - 2023. - tr. 38-45. - ISSN: 2615-9139



Ký hiệu phân loại (DDC): 616.345
Introduction: Despite many medical advances, acute lower gastrointestinal bleeding in Asia has been increasing gradually and has resulted in substantial mortality. The study aimed to describe the clinical characteristics, interventions, and outcomes of acute lower gastrointestinal bleeding in Vietnamese people. Methods: A multicenter cohort study was prospectively and retrospectively conducted in patients presenting with acute lower gastrointestinal bleeding in Vietnam. Severe lower gastrointestinal bleeding was defined as persistent bleeding within the first 24 hours and/or recurrent bleeding after 24 hours of stability accompanied by a reduction in hematocrit of ≥ 20% and/or transfusion of ≥ 2 units of red blood cells. The clinical characteristics, interventions, and adverse outcomes were recorded. Results: There were 811 patients with a male:female ratio of 1.07 and a mean age of 61 years. A total of 85.6% of patients presented with hematochezia. The common causes of acute lower gastrointestinal bleeding were hemorrhoids (28.6%), diverticulosis (9.7%), and unknown origin (16%). The rates of blood transfusion, endoscopic therapy, radiologic intervention, and surgery were 39.8%, 8.6%, 0.5%, and 7.3%, respectively. Severe lower gastrointestinal bleeding was observed in 222 (27.4%) patients. In-hospital deaths were recorded in 17 (2.1%) patients. The majority of in-hospital deaths were due to unstable comorbidities. Conclusions: Hemorrhoids were the most common cause of acute lower gastrointestinal bleeding. The rates of blood transfusion, endoscopic hemostasis, interventional radiology, and surgery were 39.8%, 8.6%, 0.5%, and 7.3%, respectively. A total of 27.4% of cases progressed to severe bleeding.
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Is the thrombocytopenia one of useful predictivemarkers of mortality in pediatric shock patients / Nguyen Ngoc Rang, Pham Huu Cong // Tạp chí Nghiên cứu Y học . - 2020. - p. 138-144. - ISSN: 2354-080X



Ký hiệu phân loại (DDC): 615
Present about platelet count is a routine laboratory measure associated with poor outcomes in adult patients with sepsis/septic shock. The aim of this study was to assess the usefulness of platelet count as a predictive marker of mortality in pediatric patients with septic shock. Over an 18-month period, 62 pediatric patients with septic shock had platelet count measured on the first day of PICU admission. The 28 day in-hospital mortality rate was 66% (41/62). Severe thrombocytopenia (≤ 50 x 109/L) was observed in 52.4% (33/62). In all patients, platelet count was independently associated with PICU mortality (OR 0.96, 95% CI 0.94, 0.99). The AUROC for thrombocytopenia to predict mortality was 0.93 (95% CI 0.87, 0.99). The AUROC of PRISM III score and pSOFA score were 0.81 (95% CI, 0.70 – 0.92) and 0.84 (95% CI, 0.74 – 0.94), respectively. Thrombocytopenia was associated with mortality in pediatric patients with septic shock and provides similar prognostic information as the more complex PRISM III and pSOFA scores.
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