Dòng Nội dung
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Comparison of the long-term efficacy of Tenofovir monotherapy versus Tenofovir and Phyllanthus Amari combination therapy : A randomized controlled trial / Huy Chung Ly, Bay Thi Nguyen, Nga Ngoc Cao, Duong Thai Nguyen, Sang Thanh Do // MedPharmRes . - 2023. - tr. 99-108. - ISSN: 2615-9139



Ký hiệu phân loại (DDC): 616.36
Introduction: Hepatitis B infection has become a social burden in over the world due to its high prevalence, while the treatments still do not offer the desired effects. Literature showed that combining traditional medicine with modern drugs was able to inhibit the proliferation of the hepatitis B virus, thus making it an effective treatment. To compare the efficacy of Tenofovir monotherapy versus Tenofovir and Phyllanthus Amari combination therapy in chronic hepatitis B patients. Materials and methods: Randomized controlled clinical trial on 200 chronic hepatitis B patients with HBeAg (+); divided into 2 groups: The combination therapy group used Phyllanthus Amari product and Tenofovir for treatment and the monotherapy group with Tenofovir. Results: The serological, biological, and virological responses in the combination therapy group were earlier than those in the monotherapy group. Statistically significant differences in serological responses between the combination therapy versus monotherapy group were achieved from the 3rd (59% versus 33%, p=0.021) to the 18 th month (99% versus 91%, p=0.029). Statistically significant differences in biochemical responses between the combination therapy versus monotherapy group were achieved from the 9th (12% versus 1%, p=0.003) to the 18th month (35% versus 21%, p=0.040). Statistically significant differences in virological response between the combination therapy versus monotherapy group were achieved from the 6th (23% versus 10%, p=0.021) to the 18th month (97% versus 88%, p=0.029). Conclusion: The combination of Tenofovir and the Phyllanthus Amari product is more effective than using only Tenofovir for treatment in chronic hepatitis B patients with HBeAg-positive.
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Effectiveness of laser acupuncture combined with physiotherapy in tennis elbow syndrome : A pre-post pilot study / Hung Le Viet Nguyen, Duy Thi Thuy Duong, Huy Chung Ly, Sang Thanh Do // MedPharmRes . - 2025. - tr. 167-179. - ISSN: 2615-9139



Ký hiệu phân loại (DDC): 615.822
Introduction: Lateral epicondylitis (LE) syndrome affects 1–3% of adults, and the effectiveness of non-invasive treat- ments remains unclear. Laser acupuncture (LA) may relieve pain as a less invasive alternative to other treatments, while physical therapy can help reduce stress on the tendons. Therefore, this study aimed to determine the potential effect of combining LA with physical therapy in patients with LE syndrome. Methods: The pilot study used a single group with 30 LE patients, who were treated by LA combined with physiother- apy exercise for four weeks. Pain levels were measured using the Visual Analog Scale (VAS), and elbow motion was assessed using a goniometer to measure the range of motion (ROM) from February to September 2024. The VAS and ROM have been compared before treatment and after treatment. Results: After 4 weeks of treatment, VAS pain scores significantly decreased from 70 mm (60–70) to 30 mm (30–40) (p<0.001). Elbow ROM extension decreased from 8 (5.7–10) to 0 (0–1) (p<0.001), and Elbow ROM flexion improved from 138.5 (134.2–140) to 142 (140–144) (p=0.002). No side effects were observed during the study. Conclusions: After four weeks, the combination of LA and physiotherapy exercises significantly reduced pain and im- proved ROM (extension and flexion) with no adverse events reported. This combined treatment offers potential analge- sic effects for LE with no side effects.
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