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Dermal absorption models in toxicology and pharmacology / J Edmond Riviere
Boca Raton : Taylor & Francis, 2005
392 pages. : illustrations ; 25 cm.
Ký hiệu phân loại (DDC): 616.5
The book begins with a review of basic principles and the in vitro and in vivo experimental approaches available for assessing dermal absorption of drugs and chemicals. This is followed by coverage of mathematical or in silico models for quantitating percutaneous absorption and the applications of these techniques to the risk assessment process. The remainder of the book explores scenarios where the unique properties of the chemicals being studied or the matrix in which they are exposed must be considered and then wraps up with a comparative analysis of chemical permeability in human and animal skin.
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