thông tin biểu ghi

ISBN 9789813144262
DDC 612.6
Nhan đề Epigenetics in human reproduction and development / Anna K. Naumova, Teruko Taketo (editor)
Thông tin xuất bản New Jersey : World Scientific, 2017
Mô tả vật lý x, 293 pages. : illustrations (some color) ; 25 cm.
Tóm tắt Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood.Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.
Từ khóa tự do Assisted reproductive technology (ART)
Từ khóa tự do Embryogenesis
Từ khóa tự do Epigenome mapping
Từ khóa tự do Non-coding RNA
Từ khóa tự do Developmental biology
Từ khóa tự do DNA methylation
Từ khóa tự do Epigenetics
Từ khóa tự do Histone modification
Từ khóa tự do Embryonic development
Từ khóa tự do Human reproduction
Khoa Khoa Y
Tác giả(bs) CN Naumova, Anna K.
Tác giả(bs) CN Taketo, Teruko
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245 |aEpigenetics in human reproduction and development / |cAnna K. Naumova, Teruko Taketo (editor)
260 |aNew Jersey : |bWorld Scientific, |c2017
300 |ax, 293 pages. : |billustrations (some color) ; |c25 cm.
520 |aEpigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood.Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.
541 |aTặng
653 |aAssisted reproductive technology (ART)
653 |aEmbryogenesis
653 |aEpigenome mapping
653 |aNon-coding RNA
653 |aDevelopmental biology
653|aDNA methylation
653|aEpigenetics
653|aHistone modification
653|aEmbryonic development
653|aHuman reproduction
690 |aKhoa Y
700 |aNaumova, Anna K.|eeditor
700 |aTaketo, Teruko|eeditor
852|a300|bQ12_Kho Mượn_02|j(2): 100570-1
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