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Handbook for Chemical Process Research and Development / Wenyi Zhao
Borca Raton, Florida : CRC Press, 2017
810 pages.
Ký hiệu phân loại (DDC): 615.19
The Handbook for Chemical Process Research and Development focuses on developing processes for chemical and pharmaceutical industries. Forty years ago there were few process research and development activities in the pharmaceutical industry,partially due to the simplicity of the drug molecules. However, with the increasing structural complexity, especially the introduction of chiral centers into the drug molecules and strict regulations set by the EMA and FDA, process R&D has become one of the critical departments for pharmaceutical companies.This book assists with the key responsibility of process chemiststo develop chemical processes for manufacturing pharmaceutical intermediates and final drug substances for clinical studies and commercial production.
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Handbook for chemical process research and development / Wenyi Zhao
Boca Raton, FL : CRC Press, 2023
xxxix, 825 pages. : illustrations ; 27 cm.
Ký hiệu phân loại (DDC): 615.19
This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies
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