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Handbook for chemical process research and development / Wenyi Zhao Boca Raton, FL : CRC Press, 2023 xxxix, 825 pages. : illustrations ; 27 cm. Ký hiệu phân loại (DDC): 615.19 This fully updated second edition reflects the significant changes in process chemistry since the first edition and includes more common process issues such as safety, cost, robustness, and environmental impact. Some areas have made notable progress such as process safety, stereochemistry, new reagents and reagent surrogates. Forty years ago there were few process research and development activities in the pharmaceutical industry, partly due to the simplicity of drug molecules. With increasing structural complexity especially the introduction of chiral centers into drug molecules and stricter regulations, process R&D has become one of the critical departments for pharmaceutical companies Số bản sách:
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