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Nanotechnology approaches for global infectious diseases / Ameya R. Kirtane, Malvika Verma, Paramesh Karandikar , Jennifer Furin, Robert Langer , Giovanni Traverso // NATURE NANOTECHNOLOGY; . - . - p.369-371. - ISSN:
Ký hiệu phân loại (DDC): 610.42
Infectious diseases are a major driver of morbidity and mortality globally. Treatment of malaria, tuberculosis and human immunodeficiency virus infection are particularly challenging, as indicated by the ongoing transmission and high mortality associated with these diseases. The formulation of new and existing drugs in nano-sized carriers promises to overcome sev- eral challenges associated with the treatment of these diseases, including low on-target bioavailability, sub-therapeutic drug accumulation in microbial sanctuaries and reservoirs, and low patient adherence due to drug-related toxicities and extended therapeutic regimens. Further, nanocarriers can be used for formulating vaccines, which represent a major weapon in our fight against infectious diseases. Here we review the current burden of infectious diseases with a focus on major drivers of morbid- ity and mortality. We then highlight how nanotechnology could aid in improving existing treatment modalities. We summarize our progress so far and outline potential future directions to maximize the impact of nanotechnology on the global population.
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Operations research methodologies / A. Ravindran
Boca Raton : CRC Press, 2009
498 pages : illustrations
Ký hiệu phân loại (DDC): 658.4034
Provides an overview of operations research methods and applications. This book explores the topics in OR/MS and examines developments in the field. It is suitable for those who use analytical techniques in decision making.
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